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[personal profile] ilex_cassine
I have had a notion about migraines for a while that they were caused by too much glutamate building up in the brain and that migraine sufferers probably have a problem clearing the stimulating chemical out. I thought this in part because MSG is a very common trigger, but other trigger foods (aged cheese, etc.) are also usually high in glutamate as well, and also because there is a "wave" of stimulation that happens in the brain with migraines, so a stimulating chemical seemed like a probable culprit there.

Turns out- I was right!! ETA: Well, at least that glutamate is a critical player. The exact mechanisms still aren't known.

I really think the key to a good migraine drug is going to be one that blocks or removes excess glutamate which will keep it from messing with our brains. There is a drug for alcoholism that supposedly has effects on glutamate levels, and I really wish that it would get into trials for migraines.

I am so excited that there might be a real solution, a real one, not just treating the symptoms solution to migraines coming up soon, there is so much good research appearing lately. A real solution would change my life.
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